Understanding Myopia Management Options: MiSight and Orthokeratology

MiSight lenses showed a 59% reduction in refractive progression and a 52% reduction in average axial elongation over a 3-year period vs single vision contact lenses, according to a study, and ortho-k lenses flatten the central cornea to correct the patient’s refractive error while creating peripheral steepening that leads to myopic defocus.

By: Patricia Fulmer, OD, FAAO

Optometric Management December 8, 2025

Clinical Report: Understanding Myopia Management Options: MiSight and Orthokeratology

Overview

MiSight lenses demonstrate significant efficacy in reducing myopia progression, with a 59% reduction in refractive progression and a 52% reduction in axial elongation over three years compared to single vision lenses. Orthokeratology (ortho-k) offers a reversible method for myopia control by reshaping the cornea overnight, providing an alternative for children needing daytime vision correction.

Background

Myopia, or nearsightedness, is a growing concern in pediatric populations, necessitating effective management strategies to prevent progression and associated ocular health risks. Recent advancements in myopia management, including the use of MiSight lenses and ortho-k, provide evidence-based options for clinicians. Understanding these interventions is crucial for optimizing treatment and improving long-term visual outcomes in children.

Data Highlights

Intervention	Refractive Progression Reduction	Axial Elongation Reduction	Study Duration
MiSight Lenses	59%	52%	3 years

Key Findings

MiSight lenses are FDA-approved for myopia control in children aged 8 to 12 years.
MiSight lenses utilize ActivControl technology to create myopic defocus, slowing axial lengthening.
Ortho-k lenses flatten the central cornea and create peripheral steepening to achieve myopic defocus.
Ortho-k lenses are a reversible option for myopia management, suitable for children who may struggle with daytime lens wear.
Both MiSight and ortho-k have shown significant reductions in myopia progression compared to traditional single vision lenses.

Clinical Implications

Practitioners should consider MiSight and ortho-k as viable options for managing myopia in pediatric patients, particularly for those at risk of rapid progression. Ongoing monitoring of axial length and refractive status is essential to evaluate treatment efficacy and make necessary adjustments.

Conclusion

The integration of MiSight lenses and ortho-k into myopia management strategies offers promising avenues for controlling myopia progression in children. Continued research and clinical application will enhance understanding and effectiveness of these interventions.

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Optometric Management