5 Key Takeaways

• 1

  Women are twice as likely as men to develop clinically significant dry eye disease, with nearly two-thirds of patients seeking care being women.

• 2

  Hormonal changes, particularly declining estrogen and progesterone during perimenopause, significantly contribute to dry eye disease.

• 3

  Cosmetic practices, such as tightlining eyeliner and eyelash extensions, can exacerbate ocular surface disease and destabilize the tear film.

• 4

  A gender-sensitive history, including inquiries about hormone therapy and cosmetic use, enhances diagnostic accuracy for dry eye disease.

• 5

  Personalized management strategies for dry eye should consider hormonal status and may involve collaboration with various healthcare providers.